BAI1 polyclonal antibody
产品名称： BAI1 polyclonal antibody
英文名称： BAI1 polyclonal antibody
产品编号： PAB25591
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BAI1.
- Immunogen:
- A synthetic peptide corresponding to 16 amino acids at C-terminus of human BAI1.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Form:
- Liquid
- Purification:
- Immunoaffinity chromatography
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (14 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 575
- Gene Name:
- BAI1
- Gene Alias:
- FLJ41988
- Gene Description:
- brain-specific angiogenesis inhibitor 1
- Omim ID:
- 602682
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq
- Other Designations:
- -
- Gene Pathway