FITC标记的PXK蛋白抗体
产品名称： FITC标记的PXK蛋白抗体
英文名称： Anti-PXK/FITC
产品编号： HZ-19688R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PXK/FITC Conjugated antibody
FITC标记的PXK蛋白抗体
| 英文名称 | Anti-PXK/FITC |
| 中文名称 | FITC标记的PXK蛋白抗体 |
| 别 名 | FLJ20335; K-ATPase; Modulator of Na. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PXK |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Function: Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. Subcellular Location: Cytoplasm. Cell membrane. Also associates with the plasma membrane. Isoform 3 is present throughout the cell. Tissue Specificity: Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. Similarity: Belongs to the protein kinase superfamily. Contains 1 protein kinase domain. Contains 1 PX (phox homology) domain. Contains 1 WH2 domain. Database links: Entrez Gene: 614093 Cow Entrez Gene: 54899 Human Entrez Gene: 218699 Mouse Entrez Gene: 306203 Rat Omim: 611450 Human SwissProt: Q7Z7A4 Human SwissProt: Q8BX57 Mouse SwissProt: Q4FZZ1 Rat Unigene: 190544 Human Unigene: 29515 Mouse Unigene: 86175 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码phox（PX）结构域蛋白，该蛋白可能参与突触传递和配体诱导的表皮生长因子内化和降解。该基因的变异可能与系统性红斑狼疮（SLE）的易感性有关。选择性剪接导致多个转录变体。[ RefSeq，2014月1日]