PTP4A1 polyclonal antibody
产品名称： PTP4A1 polyclonal antibody
英文名称： PTP4A1 polyclonal antibody
产品编号： PAB4121
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against full length recombinant PTP4A1.
- Immunogen:
- Recombinant protein corresponding to full length human PTP4A1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms.
Jeong DG, Kim SJ, Kim JH, Son JH, Park MR, Lim SM, Yoon TS, Ryu SE.J Mol Biol. 2005 Jan 14;345(2):401-13.
- 2.
- Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases.
Werner SR, Lee PA, DeCamp MW, Crowell DN, Randall SK, Crowell PL.Cancer Lett. 2003 Dec 30;202(2):201-11.
- 3.
- The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis.
Wang J, Kirby CE, Herbst R.J Biol Chem. 2002 Nov 29;277(48):46659-68. Epub 2002 Sep 13.
- Entrez GeneID:
- 7803
- Protein Accession#:
- NP_003454.1
- Gene Name:
- PTP4A1
- Gene Alias:
- DKFZp779M0721,HH72,PRL-1,PRL1,PTP(CAAX1),PTPCAAX1
- Gene Description:
- protein tyrosine phosphatase type IVA, member 1
- Omim ID:
- 601585
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq
- Other Designations:
- OTTHUMP00000016675,Protein tyrosine phosphatase IVA1,protein tyrosine phosphatase type IVA protein 1