MMP3 monoclonal antibody
产品名称： MMP3 monoclonal antibody
英文名称： MMP3 monoclonal antibody
产品编号： MAB5427
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against full length recombinant MMP3.
- Immunogen:
- Recombinant protein corresponding to full length human MMP3.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody has been selected for its ability to recognize human TIMP-3 in applications above. Approx 30 KDa band observed in cell conditioned medium and recombinant protein.
- Form:
- Lyophilized
- Isotype:
- IgG
- Storage Buffer:
- Lyophilized from PBS
- Storage Instruction:
- Store at 4°C on dry atmosphere, lyophilized antibodies are stable at least 1 year.
After reconstitution with deionized water, store at -80°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000-1:20000)
Western Blot (0.1-0. 2 ug/mL)
Immunohistochemistry (25 ug/mL)
Immunofluorescence (1:100-1:500)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family.
Apte SS, Olsen BR, Murphy G.J Biol Chem. 1995 Jun 16;270(24):14313-8.
- 2.
- Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10.
Apte SS, Hayashi K, Seldin MF, Mattei MG, Hayashi M, Olsen BR.Dev Dyn. 1994 Jul;200(3):177-97.
- 3.
- Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family.
Silbiger SM, Jacobsen VL, Cupples RL, Koski RA.Gene. 1994 Apr 20;141(2):293-7.
- Application Image
- Western Blot
- Immunohistochemistry
- Immunofluorescence
- ELISA
- Entrez GeneID:
- 4314
- Protein Accession#:
- NM_000362
- Gene Name:
- MMP3
- Gene Alias:
- CHDS6,MGC126102,MGC126103,MGC126104,MMP-3,SL-1,STMY,STMY1,STR1
- Gene Description:
- matrix metallopeptidase 3 (stromelysin 1, progelatinase)
- Omim ID:
- 185250
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
- Other Designations:
- matrix metalloproteinase 3,matrix metalloproteinase 3 (stromelysin 1, progelatinase),progelatinase,proteoglycanase,stromelysin 1,transin-1
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