KDELR3 polyclonal antibody
产品名称： KDELR3 polyclonal antibody
英文名称： KDELR3 polyclonal antibody
产品编号： PAB24233
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant KDELR3.
- Immunogen:
- Recombinant protein corresponding to amino acids of human KDELR3.
- Sequence:
- FYLYVTKGRSWDDSNADTGLRSYSSI
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Isotype:
- IgG
- Storage Buffer:
- In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 11015
- Protein Accession#:
- O43731
- Gene Name:
- KDELR3
- Gene Alias:
- ERD2L3
- Gene Description:
- KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified, and it encodes a protein highly homologous to KDELR1 and KDELR2 proteins. Two transcript variants of KDELR3 that arise by alternative splicing, and encode different isoforms of KDELR3 receptor, have been described. [provided by RefSeq
- Other Designations:
- KDEL receptor 3,OTTHUMP00000028924
- Gene Pathway