Anti-FADD Monoclonal Antibody

品牌：solarbio | 货号：K001421M

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001421M-50ul	solarbio	50ul	960.00元
K001421M-100ul	solarbio	100ul	1600.00元

英文名称 Anti-FADD Monoclonal Antibody
别名 FADD
应用 WB
稀释比例 WB 1:500.
交叉反应 Human
蛋白分子量 28kDa
Gene ID 8772
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG2a
免疫原 Recombinant human FADD protein.
性状 液体
Public Immunogen Range Recombinant human FADD protein.
Subcellular Locations Cytosol Nucleus Plasma Membrane
Swiss Prot Q13158
克隆号 5A3-C7-G9
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008]

英文名称	Anti-FADD Monoclonal Antibody
别名	FADD
应用	WB
稀释比例	WB 1:500.
交叉反应	Human
蛋白分子量	28kDa
Gene ID	8772
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG2a
免疫原	Recombinant human FADD protein.
性状	液体
Public Immunogen Range	Recombinant human FADD protein.
Subcellular Locations	Cytosol Nucleus Plasma Membrane
Swiss Prot	Q13158
克隆号	5A3-C7-G9
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008]