ITGAX monoclonal antibody, clone 3.9
产品名称： ITGAX monoclonal antibody, clone 3.9
英文名称： ITGAX monoclonal antibody, clone 3.9
产品编号： MAB5620
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGAX.
- Immunogen:
- Native purified ITGAX from human rheumatoid synovial fluid cells and fibronectin purified human monocytes.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- human CD11c.
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Isotype:
- IgG1
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- The Mac-1 and p150,95 beta 2 integrins bind denatured proteins to mediate leukocyte cell-substrate adhesion.
Davis GE.Exp Cell Res. 1992 Jun;200(2):242-52.
- 2.
- Structure and function of leukocyte integrins.
Larson RS, Springer TA.Immunol Rev. 1990 Apr;114:181-217.
- 3.
- The p150,95 molecule is a marker of human mononuclear phagocytes: comparison with expression of class II molecules.
Hogg N, Takacs L, Palmer DG, Selvendran Y, Allen C.Eur J Immunol. 1986 Mar;16(3):240-8.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 3687
- Gene Name:
- ITGAX
- Gene Alias:
- CD11C,SLEB6
- Gene Description:
- integrin, alpha X (complement component 3 receptor 4 subunit)
- Omim ID:
- 151510
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163299,integrin alpha X,integrin, alpha X (antigen CD11C (p150), alpha polypeptide),leu M5, alpha subunit,leukocyte surface antigen p150,95, alpha subunit,myeloid membrane antigen, alpha subunit,p150 95 integrin alpha chain
- Gene Pathway