CBL polyclonal antibody
产品名称： CBL polyclonal antibody
英文名称： CBL polyclonal antibody
产品编号： PAB6097
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of CBL.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human CBL.
- Sequence:
- C-REFVSISSPAHVAT
- Host:
- Goat
- Theoretical MW (kDa):
- 120
- Reactivity:
- Mouse
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.
Langdon WY, Hartley JW, Klinken SP, Ruscetti SK, Morse HC 3rd.Proc Natl Acad Sci U S A. 1989 Feb;86(4):1168-72.
- Entrez GeneID:
- 867
- Protein Accession#:
- NP_005179.2
- Gene Name:
- CBL
- Gene Alias:
- C-CBL,CBL2,RNF55
- Gene Description:
- Cas-Br-M (murine) ecotropic retroviral transforming sequence
- Omim ID:
- 165360
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
- Other Designations:
- oncogene CBL2