PDCD1 (Human) Recombinant Protein
产品名称: PDCD1 (Human) Recombinant Protein
英文名称: PDCD1 (Human) Recombinant Protein
产品编号: H00005133-H01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Purified PDCD1 (AAH74740.1, 33 a.a. - 145 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
- Transfected Cell Line:
- Human HEK293T cells
- Sequence:
- NPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVT
- Host:
- Human
- Theoretical MW (kDa):
- 17.71
- Form:
- Liquid
- Preparation Method:
- Transfection of pSuper-PDCD1 plasmid into HEK293T cell, and the expressed protein was purified by Strep-Tactin affinity column.
- Purification:
- Strep-Tactin affinity columns
- Concentration:
- > 10 ug/ml
- Activity:
- Not Tested
- Storage Buffer:
- 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- SDS-PAGE and Western Blot
Western Blot
SDS-PAGE Gel
- Application Image
- Western Blot
- Enzyme-linked Immunoabsorbent Assay
- SDS-PAGE
- Protein Interaction
- Entrez GeneID:
- 5133
- GeneBank Accession#:
- BC074740.2
- Protein Accession#:
- AAH74740.1
- Gene Name:
- PDCD1
- Gene Alias:
- CD279,PD1,SLEB2,hPD-1,hPD-l
- Gene Description:
- programmed cell death 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Addison Disease
- Alveolitis, Extrinsic Allergic
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Carcinoma, Squamous Cell
- Choriocarcinoma
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graves Disease
- Hydatidiform Mole
- Inflammation
- Kidney Diseases
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive